Saxenda - Weight Loss Injections

Saxenda - Weight Loss Injections

Saxenda is a prescription only medication used as a supporting tool in weight reduction (in combination with lifestyle and behavioural approaches) to achieve a reduction in hunger and appetite.

It contains the active ingredient Liraglutide which is a GLP-1 receptor agonist- This is similar to natural human GLP-1 which is the body’s way of communicating the sensation of feeling full to your brain. It therefore reduces feelings of hunger and increases feelings of fullness and satiety, leading to reduced food intake.

It comes in an injection pen which is administered once per day in your fatty tissues (usually your abdomen). The dose is slowly increased over the first four weeks until you reach your full maintenance dose. 

Results of Saxenda treatment are variable but we would expect you to aim for approximately 10% loss of your initial body weight in your first course of treatment.

Saxenda Lifestyle Modifications

The treatment needs to be combined with lifestyle changes including nutritional, exercise and behavioural modifications. This is essential for long-term success and will require ongoing compliance during and after your Saxenda program.

Your doctor will tell you more about the support modules available through the Weight Journey online service.

Minimum recommended lifestyle measures:

Diet: Increase your hydration levels by drinking 2-3 litres of clear fluids per day. Reduce your calorie intake by 500 kcal per day.

Exercise: Increase your exercise levels to a minimum of 150 minutes/week of moderate exercise (such as a brisk walk) or 75 minutes/week of intense exercise (where you are out of breath and are just about able to hold a conversation but unable to sing).

Behavioural: You will be required to “re-train” your relationship with food. Your doctor will arrange Cognitive Behavioural Therapy (CBD) input if required. 

Saxenda Kate

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Structure of the Saxenda Programme

We will assess you carefully to ensure you are an appropriate candidate for the treatment. Your doctor will discuss the risks and benefits and complete the necessary paperwork with yourself.

We will take a baseline measurements and complete blood tests for any patients who are deemed to require this.

Your medication will be prescribed at this stage.

You will meet with your doctor approximately a week later who will supply your Saxenda pens (approximately one months supply), a sharps box and alcohol wipes.

You will have an opportunity to clarify any further queries and then administer your first injection together.

This will be the first day of your treatment. We will also notify your GP of the treatment plan for their reference.

 

Your doctor will phone you at an agreed time to discuss your progress with Saxenda.

Further prescriptions will be arranged at this time if required as well as an question you may have answered.

You will meet with your doctor to assess your progress and complete interim measurements and/or blood tests.

We will supply one further month supply of your medication.

This is also an opportunity to replace any full sharps boxes at the clinic.

Further fortnightly telephone reviews and monthly clinic reviews will continue throughout your course of treatment.

We advise specific lifestyle support modules that will aid you in getting the most from your Saxenda treatment. 

We will explain lifestyle changes you can make in order to ensure your Saxenda treatment has maximum effectiveness.

Dose Escalation Schedule

The dose of Saxenda will be progressively increased over the initial 4 weeks of treatment until you reach your full maintenance dose of 3 mg per day which you will continue for the duration of the treatment. 

Saxenda dosing schedule

Saxenda Medical History & Consent Form

Frequently Asked Questions

Who is a good candidate for Saxenda?

Saxenda may be a good option for you to support weight loss if you are aged between 18-75 and have a BMI of 30 or above (27 or above with a weight-related medical condition).

Our Saxenda doctor will assess you carefully during the consultation to ensure Saxenda is a good option for you.

What lifestyle modifications are required throughout the treatment?

The treatment needs to be combined with lifestyle changes including nutritional, exercise and behavioural modifications. This is essential for long-term success and will require ongoing compliance during and after your Saxenda program.

Your doctor will tell you more about the support modules available through the WeightJourney online service.

How much weight can I expect to lose on Saxenda?

The results of the treatment are highly variable between individuals and the amount of weight loss and duration of treatment can therefore differ.

Our aim would be for an approximate weight loss of 10% of your starting weight during your first course of treatment. This usually translates to around 6-12kg for most patients. 

Does Saxenda interact with my other medications?

The below drugs interact with Saxenda and treatment of Saxenda should not be used concurrently:

What are the contraindications for using Saxenda?

We advise against using Saxenda if any of the below contraindications apply to you:

  • Hypersensitivity to liraglutide or to any of the excipients: disodium phosphate dihydrate, propylene glycol, phenol and water for injection.
  • Congestive heart failure New York Heart Association (NYHA) class IV
  • Aged 75 years or more
  • Treated with other products for weight management
  • Obesity secondary to endocrinological or eating disorders or to treatment with medicinal products that may cause weight gain.
  • Severe renal impairment (eGFR less than 30)
  • Any level of hepatic impairment
  • Inflammatory bowel disease
  • Diabetic gastroparesis
  • Concurrent insulin or sulfonyuria (dose may be reduced)
  • Patients on warfarin (more frequent INR monitoring required)
  • Pregnancy and breastfeeding
  • Thyroid disease
  • Personal or family history of MTC (medullary thyroid cancer) or MEN (multiple endocrine neoplasia)

Female patients: Please stop using Saxenda immediately if you think you may be pregnant. Saxenda needs to be discontinued at least 2 weeks prior to trying for pregnancy.

What will be supplied when I start the treatment?

Your Saxenda doctor will supply your pack of Saxenda (lasting roughly one month), needles and a sharps bin for safe disposal of needles.

You will also gain access to the lifestyle and behavioural support module at this point.

What are the possible side-effects from using Saxenda?

Your Saxenda doctor will supply your pack of Saxenda (lasting roughly one month), needles and a sharps bin for safe disposal of needles.

You will also gain access to the lifestyle and behavioural support module at this point.

Saxenda Side Effects
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